Within this section of The Drake & Cavendish Luxury Hotel Guide we take a close look at luxury hotels in Cayo Largo Del Sur. You'll find full contact details of each hotel including direct links to the hotels own website and reservations system. There are many advantages to booking direct with the hotel rather than through an online travel agent; the staff you speak to will have first hand knowledge of the property, they can advise you on the best rooms, and will often have access to the latest special offers.