Drake & Cavendish have an amazing selection of luxury hotels in Panama featured within this section that are perfect for a relaxing vacation to Panama. Many of the luxury hotels featured are also perfect for honeymoons, romantic breaks or special occasions. No matter what type of vacation you are planning we hope to have compiled a comprehensive list of the very best hotels in Panama for you to research.  If you’d like to search for a hotel based on your specific requirements, we invite you to read our Specialist Collections section where we have grouped hotels by category rather than destination, this section is great if you know you want a boutique hotel, or a family friendly hotel. We’d like to think we’ve done the hard work for you by grouping them together!